What kind of samples are used in the ionisation step of mass spectroscopy?

What kind of samples are used in the ionisation step of mass spectroscopy?

• A. Solid samples only
• B. Liquid samples only
• C. Gaseous samples
• D. Any physical state is acceptable

Answer: (C)

In the ionisation step of mass spectroscopy, gaseous samples are typically used because the ionisation process requires the analyte to be in a form that can be efficiently ionized and then detected based on its mass-to-charge ratio. In many mass spectrometry techniques, such as electron impact ionization, samples are vaporized and ionized in the gas phase, allowing for effective interaction with the ionizing energy. While samples can be converted from solid or liquid to gas before ionisation, the fundamental requirement during the ionization phase is that the substance must be in a gaseous state. This enables the generation of ions that can then be analyzed by the mass spectrometer. Hence, gaseous samples are optimal for this process due to their ability to travel through the ionization chamber and interact appropriately with the ionization source. This understanding highlights why gaseous samples are specifically emphasized in the ionisation step, recognizing that while samples can start in other states, they must be converted into gas to undergo successful ionization.

In the ionisation step of mass spectroscopy, gaseous samples are typically used because the ionisation process requires the analyte to be in a form that can be efficiently ionized and then detected based on its mass-to-charge ratio. In many mass spectrometry techniques, such as electron impact ionization, samples are vaporized and ionized in the gas phase, allowing for effective interaction with the ionizing energy.

While samples can be converted from solid or liquid to gas before ionisation, the fundamental requirement during the ionization phase is that the substance must be in a gaseous state. This enables the generation of ions that can then be analyzed by the mass spectrometer. Hence, gaseous samples are optimal for this process due to their ability to travel through the ionization chamber and interact appropriately with the ionization source.

This understanding highlights why gaseous samples are specifically emphasized in the ionisation step, recognizing that while samples can start in other states, they must be converted into gas to undergo successful ionization.